Bruker rapifleX MALDI-TOF-TOF mass spectrometer installed

The Department Mass Spectrometry facility has added a new Bruker rapifleX MALDI-TOF-TOF mass spectrometer to its suite of instruments.  The rapifleX purchase was made possible through an NSF MRI grant written by Dr. Carolyn Cassady.  The new mass spectrometer provides state-of-the-art capability for mass analyzing non-volatile samples, such as proteins and polymeric materials.  The instrument also brings chemical imaging capability to the facility allowing spatially resolved analysis of the chemical composition of materials.  For information on using the new rapifleX MALDI-TOF-TOF, please contact Dr. Qiaoli Liang, Mass Spectrometry Facility Manager.

Bruker rapifleX MALDI-TOF-TOF mass spectrometer

Grant to support new X-ray diffractometer

A Major Research Instrumentation (MRI) proposal from the NSF entitled, “MRI: Acquisition of a Single Crystal X-Ray Diffractometer for Structure Determination and Diffuse Scattering on Small Molecules, Macromolecules, and Materials,” has been awarded to PI Dr. Elizabeth Papish and co-PIs Dr. Jared Allred, Dr. Jack Dunkle, and Dr. Kevin Shaughnessy.  The grant will provide over $300,000 to partially support the purchase of a new single crystal X-ray diffractometer with the remaining funds coming from UA cost match.  The new instrument will expand the department’s capabilities to determine the solid state structure of small molecules, biomolecules, and solid state materials.

Dr. Pan receives UA Research Award

Dr. Shanlin Pan received the Senior Investigator award in the Physical and Biological Sciences, Mathematics, and Engineering division at the UA Faculty Research Day. Each year the Office of the Vice President for Research and Economic Development hosts the UA Faculty Research Day.  Two faculty in at both the senior and junior level are selected to receive awards in one of three areas.  Dr. Pan’s research focuses on applications of electrochemistry and spectroscopy to understanding problems in energy conversion and storage, as well as catalysis.

Conte receives presentation award

Juliana Conte, a PhD student working with Dr. Frantom, received the best overall presentation award at the 2018 Southeastern Enzyme Conference in Atlanta, GA. Juliana’s poster was entitled, “Investigation of 2-Phosphinometylmalic Acid Synthase:  A Member of the DRE-TIM Metallolyase Superfamily.

Juliana Conte won the best presentation award at the 2018 Southeast Enzyme Conference.

Randall Outstanding Undergraduate Research Awards

Congratulations to the students doing research in the Department who received Randall Outstanding Undergraduate Research Awards.
  • Amber Gomez
    Mentor: Dr. David Dixon
    Title: Computational Studies of the Electron and Fluoride Affinities of Early Actinide Oxides and Oxo-Fluoride Complexes
  • James Howard
    Mentor: Dr. Kevin Shaughnessy
    Title: Application of Air-Stable Palladium(II) Precatalysts to Suzuki Cross-Coupling Reactions and C-H Activeation of Pyridine N-Oxides
  • Addison Iszler
    Mentor: Dr. Marco Bonizzoni
    Title: Noncovalent Interactions in PAMAM Dendrimer Analogues
  • Elliot Lakner
    Mentor: Dr. David Dixon
    Title: Structural and Electronic Properties of Pd Clusters: Catalyst Models
  • Donna Xia
    Mentor: Dr. David Dixon
    Title: Actinide Aqueous Hydrolysis Reactions: Initial Steps in Actinide Aggregation
 
Donna Xia also received the Henry Pettus Randall, Jr. Scholarship as the highest rated project by a Randall Scholars Program student.

Dr. Dunkle receives NIH grant

Dr. Jack Dunkle, assistant professor in the Department of Chemistry and Biochemistry, has received a grant from the National Institutes of Health to study antibiotic resistance in collaboration with researchers at Spring Hill College in Mobile, AL.  Antibiotic resistance is a major concern as many of the commonly used antibiotic drugs become ineffective and bacteria evolve that are resistant to all available treatments.  The team will study the erythromycin resistance methyltransferase enzyme, which is one process by which bacteria become resistant to antibiotics. By understanding the mechanism for this enzyme, Dr. Dunkle and his team hope to be able to identify potential targets for drugs to combat antibiotic resistance.  UA Press Release

NSF grant to fund new MALDI-TOF instrument

The NSF has announced it will fund a proposal entitled, “MRI:  Acquisition of a high performance matrix-assisted laser ionization dual time-of-flight (MALDI/TOF-TOF) mass spectrometer (MS),” through the Major Research Implementation program.  The proposal led by Dr. Carolyn Cassady will provide funds to purchase a state of the art MALDI-TOF mass spectrometer.  The MALDI-TOF instrument will be part of the department’s Mass Spectrometry facility.  MALDI-TOF allows molecular weight characterization of non-volatile compounds, such as biomolecules and polymers.  The instrument will support researchers in the departments of Chemistry, Chemical & Biological Engineering, and Biological Sciences.

Dr. Allred receives DOE Early Career Research Grant

Dr. Jared Allred has received a 5 year, $750,000 Department of Energy Early Career research grant from the Office of Basic Energy Science and the DOE EPSCOR program.  Dr. Allred’s proposal entitled, “Investigation of Short‐Range Ordering in Transition Metal Compounds by Diffuse Scattering,” was one of 59 proposals selected for funding from over 700 submissions.  The DOE Early Career Research Program supports the development of individual research programs of outstanding scientists early in their careers and stimulates research careers in the disciplines supported by the DOE Office of Science.